HOW THE MESSENGER GOT ITS TAIL - ADDITION OF POLY(A) IN THE NUCLEUS

被引：393
作者：
WICKENS, M
机构：
[1] Department of Biochemistry, The Graduate School, College of Agriculture and Life Sciences, Madison
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期
关键词：
D O I：
10.1016/0968-0004(90)90054-F
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Most mRNAs end in a poly(A) tail, the addition of which is catalysed by a poly(A) polymerase in conjunction with a distinct factor that provides specificity for mRNAs. The reaction is dynamic, involving separable initiation, elongation and termination phases. A companion article in next month's TIBS will review the regulation of poly(A) addition and removal during early animal development. © 1990.
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页码：277 / 281
页数：5
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