EFFECT OF SCHEDULE OF ADMINISTRATION ON THE THERAPEUTIC EFFICACY OF PENICILLIN - IMPORTANCE OF THE AGGREGATE TIME PENICILLIN REMAINS AT EFFECTIVELY BACTERICIDAL LEVELS

被引：182
作者：
EAGLE, H
FLEISCHMAN, R
MUSSELMAN, AD
机构：
来源：
AMERICAN JOURNAL OF MEDICINE | 1950年 / 9卷 / 03期
关键词：
D O I：
10.1016/0002-9343(50)90425-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：280 / 299
页数：20
相关论文
共 32 条
[1]   A NEW ABSORPTION DELAYING VEHICLE FOR PENICILLIN [J].
BUCKWALTER, FH ;
DICKISON, HL .
JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION-SCIENTIFIC EDITION, 1948, 37 (11) :472-474
[2]   THE CONCENTRATION OF PENICILLIN IN VARIOUS BODY FLUIDS DURING PENICILLIN THERAPY [J].
COOKE, JV ;
GOLDRING, D .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1945, 127 (02) :80-86
[3]  
CORNFIELD J, J AM STATIST A
[4]  
CUTTING WC, 1945, J PHARMACOL EXP THER, V85, P36
[5]   THE RECOVERY OF BACTERIA FROM THE TOXIC EFFECTS OF PENICILLIN [J].
EAGLE, H .
JOURNAL OF CLINICAL INVESTIGATION, 1949, 28 (05) :832-836
[6]   THE SERUM CONCENTRATION OF PENICILLIN-G IN MICE, RABBITS, AND MEN AFTER ITS INTRAMUSCULAR INJECTION IN AQUEOUS SOLUTION [J].
EAGLE, H ;
FLEISCHMAN, R ;
MUSSELMAN, AD .
JOURNAL OF BACTERIOLOGY, 1949, 57 (01) :119-126
[7]   THE RATE OF BACTERICIDAL ACTION OF PENICILLIN INVITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS [J].
EAGLE, H ;
MUSSELMAN, AD .
JOURNAL OF EXPERIMENTAL MEDICINE, 1948, 88 (01) :99-131
[8]   THE EFFECT OF HUMAN SERUM ON THE DILUTION BIOASSAY OF PENICILLIN-G, PENICILLIN-X, AND PENICILLIN-K [J].
EAGLE, H ;
TUCKER, HA .
JOURNAL OF BACTERIOLOGY, 1948, 56 (01) :59-62
[9]   SPECULATIONS AS TO THE THERAPEUTIC SIGNIFICANCE OF THE PENICILLIN BLOOD LEVEL [J].
EAGLE, H .
ANNALS OF INTERNAL MEDICINE, 1948, 28 (02) :260-278
[10]  
EAGLE H, 1946, B JOHNS HOPKINS HOSP, V79, P168
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