CHOLERETIC AND CHOLESTATIC EFFECTS OF INFUSED BILE-SALTS IN THE RAT

被引：51

作者：

DREW, R

PRIESTLY, BG

机构：

[1] Department of Human Physiology and Pharmacology, The University of Adelaide, Adelaide, 5001, South Australia

来源：

EXPERIENTIA | 1979年 / 35卷 / 06期

关键词：

D O I：

10.1007/BF01968265

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In rats, at low infusion rates taurocholate (TC), taurochenodeoxycholate (TCDC) and taurodeoxycholate (TCD) each produced an increase in bile flow of 20-50%. However, at high infusion rates (5-20 μmoles min-1 kg-1) the cholestatic effects of the bile salts were revealed and the relative toxicity of the bile salts was seen to be TDC>TCDC>TC. © 1979 Birkhäuser Verlag.

引用

页码：809 / 811

页数：3

共 21 条

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[2]

ERLINGER S, 1974, GASTROENTEROLOGY, V66, P281

[3]

FISHER MM, 1971, LAB INVEST, V25, P88

[4]

HERZ R, 1976, SCAND J GASTROENTERO, V11, P741