IEJIMALIDE-C AND IEJIMALIDE-D, NEW ANTINEOPLASTIC 24-MEMBERED MACROLIDE SULFATES FROM THE OKINAWAN MARINE TUNICATE EUDISTOMA CF RIGIDA

被引：52
作者：
KIKUCHI, Y
ISHIBASHI, M
SASAKI, T
KOBAYASHI, J
机构：
[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN
[2] KANAZAWA UNIV,CANC RES INST,KANAZAWA,ISHIKAWA 920,JAPAN
来源：
TETRAHEDRON LETTERS | 1991年 / 32卷 / 06期
关键词：
D O I：
10.1016/S0040-4039(00)74889-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two new 24-membered macrolide sulfates, iejimalides C (1) and D (2), with antineoplastic activity have been isolated from the Okinawan marine tunicate Eudistoma cf. rigida. The structures were elucidated on the basis of spectroscopic data.
引用
收藏
页码：797 / 798
页数：2
相关论文
共 7 条
[1]   NOVEL SULFATED STEROL GLYCOSIDES FROM ASTERIAS-FORBESI [J].
FINDLAY, JA ;
HE, ZQ .
JOURNAL OF NATURAL PRODUCTS, 1990, 53 (03) :710-712
[2]   IEJIMALIDE-A AND IEJIMALIDE-B, NOVEL 24-MEMBERED MACROLIDES WITH POTENT ANTILEUKEMIC ACTIVITY FROM THE OKINAWAN TUNICATE EUDISTOMA CF RIGIDA [J].
KOBAYASHI, J ;
CHENG, JF ;
OHTA, T ;
NAKAMURA, H ;
NOZOE, S ;
HIRATA, Y ;
OHIZUMI, Y ;
SASAKI, T .
JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (26) :6147-6150
[3]   RIGIDIN, A NOVEL ALKALOID WITH CALMODULIN ANTAGONISTIC ACTIVITY FROM THE OKINAWAN MARINE TUNICATE EUDISTOMA CF RIGIDA [J].
KOBAYASHI, J ;
CHENG, JF ;
KIKUCHI, Y ;
ISHIBASHI, M ;
YAMAMURA, S ;
OHIZUMI, Y ;
OHTA, T ;
NOZOE, S .
TETRAHEDRON LETTERS, 1990, 31 (32) :4617-4620
[4]   AGELIFERINS, POTENT ACTOMYOSIN ATPASE ACTIVATORS FROM THE OKINAWAN MARINE SPONGE AGELAS SP [J].
KOBAYASHI, J ;
TSUDA, M ;
MURAYAMA, T ;
NAKAMURA, H ;
OHIZUMI, Y ;
ISHIBASHI, M ;
IWAMURA, M ;
OHTA, T ;
NOZOE, S .
TETRAHEDRON, 1990, 46 (16) :5579-5586
[5]   HYMENOSULFATE, A NOVEL STEROL SULFATE WITH CA-RELEASING ACTIVITY FROM THE CULTURED MARINE HAPTOPHYTE HYMENOMONAS SP [J].
KOBAYASHI, J ;
ISHIBASHI, M ;
NAKAMURA, H ;
OHIZUMI, Y ;
HIRATA, Y .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (01) :101-103
[6]   AMPHIDINOLIDE-E, A NOVEL ANTILEUKEMIC 19-MEMBERED MACROLIDE FROM THE CULTURED SYMBIOTIC DINOFLAGELLATE AMPHIDINIUM SP [J].
KOBAYASHI, J ;
ISHIBASHI, M ;
MURAYAMA, T ;
TAKAMATSU, M ;
IWAMURA, M ;
OHIZUMI, Y ;
SASAKI, T .
JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (10) :3421-3423
[7]   EUDISTOMIDIN-B, EUDISTOMIDIN-C, AND EUDISTOMIDIN-D - NOVEL ANTILEUKEMIC ALKALOIDS FROM THE OKINAWAN MARINE TUNICATE EUDISTOMA-GLAUCUS [J].
KOBAYASHI, J ;
CHENG, JF ;
OHTA, T ;
NOZOE, S ;
OHIZUMI, Y ;
SASAKI, T .
JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (11) :3666-3670
1