FAILURE OF VINORELBINE TO PRODUCE RESPONSES IN PRETREATED NONSMALL CELL LUNG-CANCER PATIENTS

被引：0
作者：
PRONZATO, P
LANDUCCI, M
VAIRA, F
VIGANI, A
BERTELLI, G
机构：
[1] IST NAZL RIC CANC,I-16132 GENOA,ITALY
[2] OSPED SAN ANDREA,UO ONCOL MED,LA SPEZIA,ITALY
来源：
ANTICANCER RESEARCH | 1994年 / 14卷 / 3B期
关键词：
VINORELBINE; NONSMALL CELL LUNG CANCER; 2ND-LINE CHEMOTHERAPY;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Fifteen patients with advanced non-small cell lung cancer, already, treated with first-line chemotherapy, entered a protocol of palliative second-line treatment with the hemysynthetic vinca alkaloid vinorelbine (25 mg/sm weekly for two months). No patient obtained an objective response and the trial was stopped. Toxicity was not as mild as expected, with one treatment-related death due to leukopenia. It is concluded that single-agent vinorelbine, although effective as front-line chemotherapy for non-small cell lung cancer patients, is probably is not suitable for palliative treatment of pretreated patients.
引用
收藏
页码：1413 / 1415
页数：3
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