N-METALLO IMINES - A NEW APPROACH TO ALPHA-AMINO ALCOHOLS FROM ALDEHYDES

被引：40

作者：

CAINELLI, G ^{[1
]}

GIACOMINI, D ^{[1
]}

MEZZINA, E ^{[1
]}

PANUNZIO, M ^{[1
]}

ZARANTONELLO, P ^{[1
]}

机构：

[1] CNR,CSFM,I-40126 BOLOGNA,ITALY

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 25期

关键词：

ALPHA-HYDROXY-N-TRIMETHYLSILYLIMINES; 1,2-AMINOLS; DIASTEREOSELECTIVE ADDITION TO THE AZOMETHINE CARBON;

D O I：

10.1016/0040-4039(91)80664-R

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of lithium alkyls or Grignard reagents to the in situ generated 0-protected alpha-hydroxy-N-trimethylsilylimines proceeds in good yields and highly stereocontrolled manner to produce 1,2-aminols.

引用

页码：2967 / 2970

页数：4

共 30 条

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[10]

CAINELLI G, 1990, TETRAHEDRON LETT, V32, P3481

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