A FAMILY AND POPULATION STUDY OF THE GENETIC-POLYMORPHISM OF DEBRISOQUINE OXIDATION IN A WHITE BRITISH-POPULATION

被引：490

作者：

EVANS, DAP ^{[1
]}

MAHGOUB, A ^{[1
]}

SLOAN, TP ^{[1
]}

IDLE, JR ^{[1
]}

SMITH, RL ^{[1
]}

机构：

[1] ST MARYS HOSP,SCH MED,DEPT BIOCHEM & EXPTL PHARMACOL,LONDON W2 1PG,ENGLAND

来源：

JOURNAL OF MEDICAL GENETICS | 1980年 / 17卷 / 02期

关键词：

D O I：

10.1136/jmg.17.2.102

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：102 / 105

页数：4

共 8 条

[1]

EMERY AEH, 1976, METHODOLOGY MEDICAL

[2]

IDLE JR, 1979, BRIT J PHARMACOL, V66, pP430

[3] HYPOTENSIVE RESPONSE TO DEBRISOQUINE AND HYDROXYLATION PHENOTYPE [J].

IDLE, JR ;

MAHGOUB, A ;

LANCASTER, R ;

SMITH, RL .

LIFE SCIENCES, 1978, 22 (11) :979-983

[4]

IDLE JR, 1979, BRIT J PHARMACOL, V66, pP432

[5] METABOLISM OF [C-14]-DEBRISOQUINE IN MAN [J].

IDLE, JR ;

MAHGOUB, A ;

ANGELO, MM ;

DRING, LG ;

LANCASTER, R ;

SMITH, RL .

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[6] INTERINDIVIDUAL AND INTERSPECIES VARIATION IN THE METABOLISM OF THE HALLUCINOGEN 4-METHOXYAMPHETAMINE [J].

KITCHEN, I ;

TREMBLAY, J ;

ANDRE, J ;

DRING, LG ;

IDLE, JR ;

SMITH, RL ;

WILLIAMS, RT .

XENOBIOTICA, 1979, 9 (07) :397-404

[7] POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN [J].

MAHGOUB, A ;

IDLE, JR ;

DRING, LG ;

LANCASTER, R ;

SMITH, RL .

LANCET, 1977, 2 (8038) :584-586

[8] POLYMORPHISM OF CARBON OXIDATION OF DRUGS AND CLINICAL IMPLICATIONS [J].

SLOAN, TP ;

MAHGOUB, A ;

LANCASTER, R ;

IDLE, JR ;

SMITH, RL .

BRITISH MEDICAL JOURNAL, 1978, 2 (6138) :655-657

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