PLACENTAL GROWTH-HORMONE IN SHEEP - PURIFICATION, PROPERTIES AND VARIATIONS

被引：16
作者：
MARTAL, J
机构：
来源：
ANNALES DE BIOLOGIE ANIMALE BIOCHIMIE BIOPHYSIQUE | 1978年 / 18卷 / 01期
关键词：
D O I：
10.1051/rnd:19780107
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The purification of a placental growth-promoting hormone, Ovine Chorionic Somatomammotropin (OCS), and its main physicochemical, immunologic and biological properties were studied. OCS diffused into the amniotic fluid and was excreted into the allantoid fluid, but its concentrations in these compartments remained very low by comparison with the maternal or fetal serum. The total growth activity, as measured by radio-receptor assay in fetal serum, remained almost constant from day 60 to day 140 of pregnancy. Thus fetal weight increase and total amounts of growth-promoting activities present (OCS + OGH) per fetus were about proportional.
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页码：45 / 51
页数：7
相关论文
共 19 条
[1]   PLASMA GROWTH HORMONE CONCENTRATION OF FOETAL LAMB [J].
BASSETT, JM ;
THORBURN, GD ;
WALLACE, ALC .
JOURNAL OF ENDOCRINOLOGY, 1970, 48 (02) :251-+
[2]   PURIFICATION AND CHARACTERIZATION OF OVINE PLACENTAL LACTOGEN [J].
CHAN, JSD ;
ROBERTSON, HA ;
FRIESEN, HG .
ENDOCRINOLOGY, 1976, 98 (01) :65-76
[3]  
DJIANE J, 1975, CR ACAD SCI D NAT, V280, P2785
[4]  
DJIANE J, 1975, P INT S GROWTH REL S, V1, P128
[5]  
DUBOIS M, 1976, 5TH P INT C END HAMB, P25
[6]  
FELLOWS RE, 1976, GROWTH HORMONE RELAT, P315
[7]   EVIDENCE FOR HOMOLOGY BETWEEN OVINE AND HUMAN PLACENTAL LACTOGENS [J].
HANDWERGER, S ;
MAURER, W ;
BARRETT, J ;
HURLEY, T ;
FELLOWS, RE .
ENDOCRINE RESEARCH COMMUNICATIONS, 1974, 1 (04) :403-413
[8]  
JOST A, 1951, Biol Med (Paris), V40, P205
[9]   TEMPORAL PATTERN OF PLACENTAL LACTOGEN AND PROGESTERONE SECRETION IN SHEEP [J].
KELLY, PA ;
ROBERTSON, HA ;
FRIESEN, HG .
NATURE, 1974, 248 (5447) :435-437
[10]   EFFECTS OF ELECTROCOAGULATION OF FOETAL LAMB HYPOPHYSIS ON GROWTH AND DEVELOPMENT [J].
LIGGINS, GC ;
KENNEDY, PC .
JOURNAL OF ENDOCRINOLOGY, 1968, 40 (03) :371-+
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