STIMULATION OF MACROMOLECULAR PROCESSES IN BSC CELLS DUE TO MEDIUM REPLENISHMENT

被引：26
作者：
BECKER, Y
LEVITT, J
机构：
[1] Department of Virology, Hebrew University-Hadassah Medical School, Jerusalem
来源：
EXPERIMENTAL CELL RESEARCH | 1968年 / 51卷 / 01期
关键词：
D O I：
10.1016/0014-4827(68)90156-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Heteroploid BSC1 cells form monolayers in vitro and cease to grow within three to four days. The addition of fresh medium triggers off a chain of events which leads to DNA synthesis and cell duplication. The synthesis of proteins and RNA is stimulated, reaching a maximal rate 30 min after medium replenishment. The rate of protein synthesis again increases at 120 min. Inhibition of RNA synthesis affects protein synthesis, and prevention of protein formation inhibits both RNA and DNA synthesis. © 1968.
引用
收藏
页码：27 / &
相关论文
共 11 条
[1]   OBSERVATIONS ON THE SOCIAL BEHAVIOUR OF CELLS IN TISSUE CULTURE .2. MONOLAYERING OF FIBROBLASTS [J].
ABERCROMBIE, M ;
HEAYSMAN, JEM .
EXPERIMENTAL CELL RESEARCH, 1954, 6 (02) :293-306
[2]   RNA SYNTHESIS IN CULTURED CHICK EMBRYO FIBROBLASTS [J].
BECKER, Y .
EXPERIMENTAL CELL RESEARCH, 1967, 47 (03) :554-&
[3]   RNA AND PROTEIN SYNTHESIS REQUIRED FOR ENTRY OF CELLS INTO MITOSIS AND DURING MITOTIC CYCLE [J].
DONNELLY, GM ;
SISKEN, JE .
EXPERIMENTAL CELL RESEARCH, 1967, 46 (01) :93-&
[4]   AMINO ACID METABOLISM IN MAMMALIAN CELL CULTURES [J].
EAGLE, H .
SCIENCE, 1959, 130 (3373) :432-437
[5]  
GILBERT WALTER, 1963, JOUR MOLECULAR BIOL, V6, P389, DOI 10.1016/S0022-2836(63)80051-0
[6]  
HOPPS HE, 1962, FED PROC, V21, P454
[7]   CONTACT INHIBITION MACROMOLECULAR SYNTHESIS AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS [J].
LEVINE, EM ;
BECKER, Y ;
BOONE, CW ;
EAGLE, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 53 (02) :350-&
[8]   STUDIES OF LIFE CYCLE OF MAMMALIAN CELLS [J].
PUCK, TT .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1964, 29 :167-&
[9]   DEMONSTRATION OF AN UNSTABLE RNA AND OF A PRECURSOR TO RIBOSOMAL RNA IN HELA CELLS [J].
SCHERRER, K ;
DARNELL, JE ;
LATHAM, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1963, 49 (02) :240-&
[10]   CONTROL OF DNA SYNTHESIS IN MAMMALIAN CELLS IN CULTURE [J].
TAYLOR, EW .
EXPERIMENTAL CELL RESEARCH, 1965, 40 (02) :316-&
12