THE PORCINE INTESTINAL RECEPTOR FOR ESCHERICHIA-COLI K88-ALPHA-B, K88-ALPHA-C - REGIONAL LOCALIZATION ON CHROMOSOME-13 AND INFLUENCE OF IGG RESPONSE TO THE K88 ANTIGEN

被引：73

作者：

EDFORSLILJA, I ^{[1
]}

GUSTAFSSON, U ^{[1
]}

DUVALIFLAH, Y ^{[1
]}

ELLERGREN, H ^{[1
]}

JOHANSSON, M ^{[1
]}

JUNEJA, RK ^{[1
]}

MARKLUND, L ^{[1
]}

ANDERSSON, L ^{[1
]}

机构：

[1] INRA,CTR RECH JOUY EN JOSAS,ECOL & PHYSIOL SYST DIGEST LAB,F-78352 JOUY EN JOSAS,FRANCE

来源：

ANIMAL GENETICS | 1995年 / 26卷 / 04期

关键词：

ANTIBODY RESPONSE; CHROMOSOME; 13; ESCHERICHIA COLI; K88; RECEPTOR; LINKAGE; PIG;

D O I：

10.1111/j.1365-2052.1995.tb03250.x

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The loci encoding the porcine intestinal receptors for Escherichia call K88ab and K88ac (K88abR and K88acR) were firmly assigned to chromosome 13 by linkage analysis using a three-generation pedigree. The linear order of these loci and seven other markers on chromosome 13 was determined by multipoint analyses, The K88abR and K88acR loci were tightly linked (theta ($) over cap = 0.01, Z ($) over cap = 41.06) with the K88abR locus localized 7.4 cM (sex average) proximal to the transferrin locus. The results, together with previous reports from two other groups, provide an unequivocal assignment of the K88 receptor loci to chromosome 13, and reject a previous assignment to chromosome 4. Pigs possessing the receptor had a slightly higher specific IgG response to the K88 antigen after an intramuscular immunization with an E. coli vaccine.

引用

页码：237 / 242

页数：6

共 39 条

[1] GENETIC-MAPPING OF QUANTITATIVE TRAIT LOCI FOR GROWTH AND FATNESS IN PIGS [J].

ANDERSSON, L ;

HALEY, CS ;

ELLEGREN, H ;

KNOTT, SA ;

JOHANSSON, M ;

ANDERSSON, K ;

ANDERSSONEKLUND, L ;

EDFORSLILJA, I ;

FREDHOLM, M ;

HANSSON, I ;

HAKANSSON, J ;

LUNDSTROM, K .

SCIENCE, 1994, 263 (5154) :1771-1774

[2]

BERTIN AM, 1991, AM J VET RES, V52, P45

[3] ADHESIVE FIMBRIAE PRODUCED INVIVO BY ESCHERICHIA-COLI O139-K12(B)-H1 ASSOCIATED WITH ENTEROTOXEMIA IN PIGS [J].

BERTSCHINGER, HU ;

BACHMANN, M ;

METTLER, C ;

POSPISCHIL, A ;

SCHRANER, EM ;

STAMM, M ;

SYDLER, T ;

WILD, P .

VETERINARY MICROBIOLOGY, 1990, 25 (2-3) :267-281

[4] INHERITANCE OF K88-MEDIATED ADHESION OF ESCHERICHIA-COLI TO JEJUNAL BRUSH-BORDERS IN PIGS - A GENETIC-ANALYSIS [J].

BIJLSMA, IGW ;

BOUW, J .

VETERINARY RESEARCH COMMUNICATIONS, 1987, 11 (06) :509-518

[5] DIFFERENT PIG PHENOTYPES AFFECT ADHERENCE OF ESCHERICHIA-COLI TO JEJUNAL BRUSH-BORDERS BY K88AB-ANTIGEN, K88AC-ANTIGEN, OR K88AD-ANTIGEN [J].

BIJLSMA, IGW ;

DENIJS, A ;

VANDERMEER, C ;

FRIK, JF .

INFECTION AND IMMUNITY, 1982, 37 (03) :891-894

[6] K88 VARIANTS K88AB, K88AC AND K88AD IN ORAL VACCINATION OF DIFFERENT PORCINE ADHESIVE PHENOTYPES - IMMUNOLOGICAL ASPECTS [J].

BIJLSMA, IGW ;

VANHOUTEN, M ;

FRIK, JF ;

RUITENBERG, EJ .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1987, 16 (3-4) :235-250

[7] THE PREVALENCE OF DIFFERENT PORCINE PHENOTYPES IN THE NETHERLANDS CONCERNING ADHERENCE OF K88-POSITIVE ESCHERICHIA-COLI TO INTESTINAL EPITHELIUM [J].

BIJLSMA, IGW ;

DENIJS, A ;

FRIK, JF .

VETERINARY QUARTERLY, 1985, 7 (03) :246-248

[8]

Bonneau M., 1990, Annales de Recherches Veterinaires, V21, P302

[9] THE DISTRIBUTION AND STABILITY OF ESCHERICHIA-COLI K88 RECEPTOR IN THE GASTROINTESTINAL-TRACT OF THE PIG [J].

CHANDLER, DS ;

MYNOTT, TL ;

LUKE, RKJ ;

CRAVEN, JA .

VETERINARY MICROBIOLOGY, 1994, 38 (03) :203-215

[10]

CHAPPUIS JP, 1984, GENET SEL EVOL, V16, P385, DOI 10.1186/1297-9686-16-3-385

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