EPITOPE MAPPING

被引：44

作者：

HORSFALL, AC ^{[1
]}

HAY, FC ^{[1
]}

SOLTYS, AJ ^{[1
]}

JONES, MG ^{[1
]}

机构：

[1] ST GEORGE HOSP,SCH MED,DEPT CELLULAR & MOLEC SCI,DIV IMMUNOL,LONDON SW17 0RE,ENGLAND

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 07期

关键词：

PEPTIDE-SYNTHESIS; DETERMINANT; PREDICTION; MOLECULES; SEQUENCE; LIGANDS; LIBRARY;

D O I：

10.1016/0167-5699(91)90029-S

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immune response to extrinsic and intrinsic antigens involves specific antigen receptors on T and B cells. The precise antigenic determinants, or epitopes, recognized by these receptors are discrete sequences within the native antigen. The ability to identify and manufacture key epitopes in the immune response has important implications for disease diagnosis and immunointervention. Consequently, increasingly sophisticated technologies are being applied to epitope mapping. This report from a recent workshop gives a balanced view of progress to date and the challenges ahead.

引用

页码：211 / 213

页数：3

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