EFFICACY STUDIES ON A CANARYPOX-RABIES RECOMBINANT VIRUS

被引:129
|
作者
TAYLOR, J
TRIMARCHI, C
WEINBERG, R
LANGUET, B
GUILLEMIN, F
DESMETTRE, P
PAOLETTI, E
机构
[1] VIROGENET CORP,465 JORDAN RD,RENSSELAER TECHNOL PK,TROY,NY 12180
[2] NEW YORK STATE DEPT HLTH,WADSWORTH CTR LABS & RES,ALBANY,NY 12201
[3] RHONE MERIEUX,F-69007 LYONS,FRANCE
关键词
RECOMBINANT; CANARYPOX; RABIES; FOWLPOX; VACCINIA;
D O I
10.1016/0264-410X(91)90152-V
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recombinant avipox viruses have been developed expressing the rabies glycoprotein gene. A fowlpox-rabies recombinant has previously been shown to be protective against live rabies virus challenge in a number of non-avian species1. This report describes the development of a canarypox-rabies recombinant. A comparison is made of the protective efficacy of this recombinant with other pox-rabies recombinants.
引用
收藏
页码:190 / 193
页数:4
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