Metabolic Syndrome and Asthma

被引:31
作者
Garmendia, Jenny V. [1 ]
Moreno, Dolores [2 ]
Garcia, Alexis H. [1 ]
De Sanctis, Juan B. [1 ]
机构
[1] Univ Cent Venezuela, Inst Inmunol, Fac Med, Focis Ctr Excellence, Caracas, Venezuela
[2] Univ Cent Venezuela, Fac Med, Catedra Patol Gen & Fisiopatol, Caracas, Venezuela
关键词
Asthma; dyslipidemia; hypertension; immune response; insulin resistance; metabolic syndrome;
D O I
10.2174/1872214807666140107151023
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Metabolic syndrome (MetS) is a syndrome that involves at least three disorders dyslipidemia, insulin resistance, obesity and/or hypertension. MetS has been associated with several chronic diseases in the adulthood; however, in the recent years, the syndrome was redefined in children. Girls with early menarche and asthma, and children with MetS and asthma that reach adulthood appear to have higher risk to develop severe or difficult to control asthma and a higher probability to suffer cardiovascular diseases. It has been proposed that patients with MetS and endocrinological disorders should be considered a different entity in which pharmacologic treatment should be adjusted according to the individual. Recent patents on the field have addressed new issues on how endocrine control should be managed along with asthma therapeutics. In the near future, new approaches should decrease the high morbidity and mortality associated to these types of patients.
引用
收藏
页码:60 / 66
页数:7
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