OTITIS MEDIA TREATMENTS IN CHILDREN: SYSTEMATIC REVIEW IN LITERATURE

被引:0
作者
Yamani, Ibtihal Tariq [1 ]
Almansaf, Jumanah Ahmed [2 ]
Alharthi, Reyof Saeed [3 ]
Alosaimi, Jazi Abdullah [4 ]
Alajlouni, Dana Manhal [5 ]
Almalki, Malek Abdulrahman [6 ]
Alojayan, Abdulelah Abdullah [7 ]
Al Khalaf, Mohammed Baqer [7 ]
Alharbi, Nassrain Khalid [8 ]
Bin Hassan, Haya Mohammed [5 ]
机构
[1] Umm Al Qura Univ, Mecca, Saudi Arabia
[2] Almaarefa Univ, Riyadh, Saudi Arabia
[3] Taif Univ, At Taif, Saudi Arabia
[4] King Abdulaziz Univ, Rabigh, Saudi Arabia
[5] Princess Nourah Bint Abdulrahman Univ, Riyadh, Saudi Arabia
[6] Taibah Univ, Almadina Almunawara, Saudi Arabia
[7] King Faisal Univ, Al Hasa, Saudi Arabia
[8] Ibn Sina Natl Coll Med Studies, Jeddah, Saudi Arabia
来源
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2018年 / 5卷 / 12期
关键词
antibiotics; otitis media; children;
D O I
10.5281/zenodo.2447279
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This review is aiming to systematically summarize the literature on Otitis Media treatments in Children. The present review was conducted by searching in Medline, Embase, Web of Science, Science Direct, BMJ journal and Google Scholar for, researches, review articles and reports, published over the past years. Books published on Management of Otitis Media treatments in Children. If several studies had similar findings, we randomly selected one or two to avoid repetitive. Based on findings and results this review found All included RCTs had some methodological flaws. Three trials recruited a representative patient spectrum (Significant effect modifications were noted for otorrhoea, and for age and bilateral acute otitis media. In children younger than 2 years of age with bilateral acute otitis media, 55% of controls and 30% on antibiotics still had pain, fever, or both at 3-7 days, with a rate difference between these groups of -25% (95% CI -36% to -14%), resulting in a number-needed-to-treat (NNT) of four children. We identified no significant differences for age alone. In children with otorrhoea the rate difference and NNT, respectively, were -36% (-53% to -19%) and three, whereas in children without otorrhoea the equivalent values were -14% (-23% to -5%) and eight.6 Antibiotics seem to be most beneficial in children younger than 2 years of age with bilateral acute otitis media, and in children with both acute otitis media and otorrhoea. For most other children with mild disease an observational policy seems justified.
引用
收藏
页码:16626 / 16630
页数:5
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