TYPE-IV COLLAGEN AND LAMININ IN THE SYNOVIAL INTIMAL LAYER - AN IMMUNOHISTOCHEMICAL STUDY

被引：49

作者：

POLLOCK, LE ^{[1
]}

LALOR, P ^{[1
]}

REVELL, PA ^{[1
]}

机构：

[1] UNIV LONDON LONDON HOSP, COLL MED, BONE & JOINT RES UNIT, LONDON E1 1BB, ENGLAND

来源：

RHEUMATOLOGY INTERNATIONAL | 1990年 / 9卷 / 06期

关键词：

Basement membrane; Laminin; Synovium; Type IV collagen;

D O I：

10.1007/BF00541324

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The distribution of type IV collagen and laminin in the intimal layer of rheumatoid, osteoarthritic, traumatic and normal human synovium was determined by immunohistochemistry using polyclonal and monoclonal antibodies. All samples showed a similar pattern of labelling with type IV collagen and laminin present around the synovial intimal cells. Type IV collagen has previously only been identified in association with basement membranes which are not found at this site. Two major basement membrane components around synovial cells suggest the formation of a modified basement membrane-like structure. © 1990 Springer-Verlag.

引用

页码：277 / 280

页数：4

共 17 条

[1] ELECTRON MICROSCOPY OF HUMAN SYNOVIAL MEMBRANE [J].

BARLAND, P ;

NOVIKOFF, AB ;

HAMERMAN, D .

JOURNAL OF CELL BIOLOGY, 1962, 14 (02) :207-+

[2] LAMININ AND FIBRONECTIN IN CELL-ADHESION - ENHANCED ADHESION OF CELLS FROM REGENERATING LIVER TO LAMININ [J].

CARLSSON, R ;

ENGVALL, E ;

FREEMAN, A ;

RUOSLAHTI, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04) :2403-2406

[3] IDENTIFICATION OF SITES IN COLLAGEN ALPHA-CHAINS THAT BIND SERUM ANTI-GELATIN FACTOR (COLD-INSOLUBLE GLOBULIN) [J].

DESSAU, W ;

ADELMANN, BC ;

TIMPL, R ;

MARTIN, GR .

BIOCHEMICAL JOURNAL, 1978, 169 (01) :55-59

[4]

Ghadially F. N, 1983, FINE STRUCTURE SYNOV

[5]

GRAABECK PM, 1988, THESIS AARHUS U DENM

[6] EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN PROXIMAL TUBULES OF MOUSE KIDNEY - ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE [J].

GRAHAM, RC ;

KARNOVSKY, MJ .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1966, 14 (04) :291-+

[7] ROLE OF COLLAGENOUS MATRICES IN THE ADHESION AND GROWTH OF CELLS [J].

KLEINMAN, HK ;

KLEBE, RJ ;

MARTIN, GR .

JOURNAL OF CELL BIOLOGY, 1981, 88 (03) :473-485

[8] LAMININ PROMOTES NEURITIC REGENERATION FROM CULTURED PERIPHERAL AND CENTRAL NEURONS [J].

MANTHORPE, M ;

ENGVALL, E ;

RUOSLAHTI, E ;

LONGO, FM ;

DAVIS, GE ;

VARON, S .

JOURNAL OF CELL BIOLOGY, 1983, 97 (06) :1882-1890

[9] ULTRASTRUCTURAL CHARACTERIZATION OF MACROPHAGES (TYPE-A CELLS) IN THE SYNOVIAL LINING [J].

MAPP, PI ;

REVELL, PA .

RHEUMATOLOGY INTERNATIONAL, 1988, 8 (04) :171-176

[10] FIBRONECTIN PRODUCTION BY SYNOVIAL INTIMAL CELLS [J].

MAPP, PI ;

REVELL, PA .

RHEUMATOLOGY INTERNATIONAL, 1985, 5 (05) :229-237

← 1 2 →