MOLECULAR-CONFORMATIONS OF MET-ENKEPHALIN - COMPARISON OF ZWITTERIONIC AND CATIONIC FORMS

被引：49
作者：
JONES, CR
GARSKY, V
GIBBONS, WA
机构：
[1] UNIV WISCONSIN, COLL AGR & LIFE SCI, DEPT BIOCHEM, MADISON, WI 53706 USA
[2] UNIV WISCONSIN, COLL AGR & LIFE SCI, INST ENZYME, MADISON, WI 53706 USA
[3] WYETH LABS INC, RADNOR, PA 19087 USA
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1977年 / 76卷 / 03期
关键词：
D O I：
10.1016/0006-291X(77)91546-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Apparent discrepancies in published assignments of the PMR spectrum of Met5-enkephalin were due to the existence of 2 forms, cationic and zwitterionic. The PMR parameters of these 2 forms indicated different secondary conformations. The PMR parameters of the zwitterionic form were indicative of a 2-5 .beta.-I turn but no secondary conformation could be suggested for the cationic form with the present data.
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页码：619 / 625
页数：7
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