TRANSCRIPTIONAL REGULATION OF THE IL-2 GENE

被引：501

作者：

JAIN, J ^{[1
]}

LOH, C ^{[1
]}

RAO, A ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 03期

关键词：

D O I：

10.1016/0952-7915(95)80107-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The past two years have seen significant advances in our understanding of IL-2 gene transcription. Many of the relevant transcription factors have been identified, the intracellular mechanisms regulating their functions are being elucidated, and the multiple roles oi calcineurin are beginning to be appreciated.

引用

页码：333 / 342

页数：10

共 50 条

[21] Human CD94 gene expression : Dual promoters differing in IL-2 responsiveness, alternative transcripts and post transcriptional regulation
Coligan, JE
Maasho, K
Borrego, F
Lieto, LD
FASEB JOURNAL, 2003, 17 (07): : C97 - C98
[22] IL-2 REGULATION OF SOLUBLE IL-2 RECEPTOR LEVELS FOLLOWING THERMAL-INJURY
TEODORCZYKINJEYAN, JA
SPARKES, BG
LALANI, S
PETERS, WJ
MILLS, GB
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1992, 90 (01): : 36 - 42
[23] REGULATION OF IL-2 RECEPTOR (TAC) GENE-EXPRESSION - THE BINDING OF 2 INDUCIBLE NUCLEAR PROTEINS TO DISCRETE PROMOTER SEQUENCES CORRELATES WITH TRANSCRIPTIONAL ACTIVATION
LOWENTHAL, JW
BOHNLEIN, E
GREENE, WC
CLINICAL RESEARCH, 1988, 36 (03): : A443 - A443
[24] STRUCTURE AND REGULATION OF THE HUMAN IL-2 RECEPTOR
GREENE, WC
BOHNLEIN, E
SIEKEVITZ, M
BALLARD, DW
FRANZA, BR
LOWENTHAL, JW
MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION II, 1989, 254 : 55 - 60
[25] Regulation of c-maf by IL-2
Rani, Aradhana
Kelly, Audrey
Berhan, Lemlem Tewolde
Jurevic, Stipo
Ragheb, Jack
Lavender, Paul
John, Susan
CYTOKINE, 2009, 48 (1-2) : 11 - 11
[26] IL-2 dependent expression of genes involved in cytoskeleton organization, oncogene regulation and transcriptional control.
Herblot, S
Chastagner, P
Samady, L
Moreau, JL
Demaison, C
Froussard, P
Liu, X
Bonnet, J
Thèze, J
FASEB JOURNAL, 1999, 13 (05): : A1142 - A1142
[27] Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15 and IL-12 in Nk and T cells.
Azzoni, L
Zatsepina, O
Abebe, B
Bennett, IM
Kanakaraj, P
Perussia, B
EUROPEAN CYTOKINE NETWORK, 1998, 9 (03) : 416 - 416
[28] Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells
Zhao, W
Schafer, R
Barnett, JB
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1999, 154 (02) : 153 - 159
[29] IL-2 anitsense oligonucleotides block IL-2 gene expression and heart allograft rejection
Tian, L
Qu, XM
Wang, ME
Bennett, FC
Stepkowski, SM
TRANSPLANTATION, 1999, 67 (09) : S570 - S570
[30] 2 REGIONS WITHIN THE HUMAN IL-2 GENE PROMOTER ARE IMPORTANT FOR INDUCIBLE IL-2 EXPRESSION
WILLIAMS, TM
EISENBERG, L
BURLEIN, JE
NORRIS, CA
PANCER, S
YAO, D
BURGER, S
KAMOUN, M
KANT, JA
JOURNAL OF IMMUNOLOGY, 1988, 141 (02): : 662 - 666

← 1 2 3 4 5 →