MILD STEREOSELECTIVE SYNTHESES OF THIOGLYCOSIDES UNDER PTC CONDITIONS AND THEIR USE AS ACTIVE AND LATENT GLYCOSYL DONORS

被引：60

作者：

CAO, SD ^{[1
]}

MEUNIER, SJ ^{[1
]}

ANDERSSON, FO ^{[1
]}

LETELLIER, M ^{[1
]}

ROY, R ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT CHEM,OTTAWA K1N 6N5,ON,CANADA

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 11期

关键词：

D O I：

10.1016/S0957-4166(00)86308-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Mild and stereoselective arylthio glycoside syntheses were accomplished by inversion of configuration of glycosyl halides under phase transfer catalyzed conditions. Under such conditions, aryl alpha-thiosialosides having electron donating and withdrawing substituents were evaluated as active and latent thioglycosyl donors. A sialyl-alpha-(2-->6)-galactoside was prepared in good yield using the above strategy.

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页码：2303 / 2312

页数：10

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