IDENTIFICATION OF MYENTERIC NEURONS WHICH PROJECT TO THE MUCOSA OF THE GUINEA-PIG SMALL-INTESTINE

被引：111
作者：
SONG, ZM
BROOKES, SJH
COSTA, M
机构：
[1] FLINDERS UNIV,DEPT PHYSIOL,GPO BOX 2100,ADELAIDE 5001,AUSTRALIA
[2] FLINDERS UNIV,CTR NEUROSCI,ADELAIDE 5001,AUSTRALIA
来源：
NEUROSCIENCE LETTERS | 1991年 / 129卷 / 02期
关键词：
ENTERIC; MYENTERIC PLEXUS; MUCOSA; INTESTINE; IMMUNOHISTOCHEMISTRY; RETROGRADE TRANSPORT; DII;
D O I：
10.1016/0304-3940(91)90484-B
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Myenteric neurons which innervate the mucosa of the guinea-pig ileum were characterized by combining retrograde transport of DiI in vitro with immunohistochemistry. Of DiI-labelled myenteric neurons, 43% were immunoreactive for calbindin and substance P, 25% were immunoreactive for calbindin alone, and 18% were immunoreactive for substance P alone. These 3 classes of neurons had Dogiel Type II morphology and are probably sensory neurons. Two classes of probable secretomotor neurons were characterized by immunoreactivity for neuropeptide Y (4%) and vasoactive intestinal peptide (2%). These 5 classes of myenteric neurons represent over 90% of the retrogradely labelled myenteric neurons that project to the mucosa.
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页码：294 / 298
页数：5
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