HIPPOCAMPAL KINDLING ALTERS THE CONCENTRATION OF GLIAL FIBRILLARY ACIDIC PROTEIN AND OTHER MARKER PROTEINS IN RAT-BRAIN

被引：49
作者：
HANSEN, A
JORGENSEN, OS
BOLWIG, TG
BARRY, DI
机构：
[1] RIGSHOSP,INST NEUROPSYCHIAT,DK-2100 COPENHAGEN,DENMARK
[2] RIGSHOSP,NEUROBIOL RES GRP,DK-2100 COPENHAGEN,DENMARK
来源：
BRAIN RESEARCH | 1990年 / 531卷 / 1-2期
关键词：
Amygdala; Brain protein; D3-protein; Glial fibrillary acidic protein; Hippocampus; Kindling; Neural cell adhesion molecule; Neuron specific enolase; Pyriform cortex; Synaptic remodeling;
D O I：
10.1016/0006-8993(90)90791-9
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The effect of hippocampal kindling on neuronal and glial marker proteins was studied in the rat by immunochemical methods. In hippocampus, pyriform cortex and amygdala there was an increase in glial fibrillary acidic protein (GFAP), indicating reactive gliosis, and an increase in the glycolytic enzyme NSE, suggesting increased anaerobic metabolism. Neural cell adhesion molecule (NCAM) decreased in pyriform cortex and amygdala of kindled rats, indicating neuronal degeneration. © 1990.
引用
收藏
页码：307 / 311
页数：5
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