ANTITHROMBIN-3 - PROTECTION AGAINST DEATH AFTER INJECTION OF THROMBOPLASTIN

被引：31

作者：

MANN, LT

JENSENIUS, JC

SIMONSEN, M

ABILDGAARD, U

机构：

[1] Institute for Experimental Immunology, 2100 Copenhagen Ø

[2] Haematological Research Laboratory, Ullevaal Hospital

来源：

SCIENCE | 1969年 / 166卷 / 3904期

关键词：

D O I：

10.1126/science.166.3904.517

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Intravenous injection of autologous lipoprotein (thromboplastin) or thrombin produced a lethal, hemorrhagic syndrome in chicken embryos. The embryos could be protected from this fatal result by injection of antithrombin III, an alpha2-globulin (molecular weight 60,000 to 80,000) purified from human, bovine, and guinea pig blood. Heparin also protected the embryos, but other inhibitors were less protective.

引用

页码：517 / +

页数：1

共 9 条

[1] HIGHLY PURIFIED ANTITHROMBIN 3 WITH HEPARIN COFACTOR ACTIVITY PREPARED BY DISC ELECTROPHORESIS [J].