SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 20-DEOXO-20-(3,5-DIMETHYLPIPERIDIN-1-YL)DESMYCOSIN (TILMICOSIN, EL-870) AND RELATED CYCLIC AMINO DERIVATIVES

被引：71
作者：
DEBONO, M
WILLARD, KE
KIRST, HA
WIND, JA
CROUSE, GD
TAO, EV
VICENZI, JT
COUNTER, FT
OTT, JL
OSE, EE
OMURA, S
机构：
[1] KITASATO INST,MINATO KU,TOKYO 108,JAPAN
[2] KITASATO INST,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN
来源：
JOURNAL OF ANTIBIOTICS | 1989年 / 42卷 / 08期
关键词：
D O I：
10.7164/antibiotics.42.1253
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：1253 / 1267
页数：15
相关论文
共 20 条
[1]  
BRIGHT GM, 1985, Patent No. 136831
[2]   THE BEHAVIOR OF ALIPHATIC ALDEHYDES IN THE LEUCKART WALLACH REACTION [J].
DEBENNEVILLE, PL ;
MACARTNEY, JH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1950, 72 (07) :3073-3075
[3]  
DEBONO M, 1985, 2KTH INT C ANT AG CH, V1145, P302
[4]  
Hamill R. L., 1965, U.S. Pat., Patent No. 3178341
[5]  
HAMILL RL, 1961, ANTIBIOT CHEMOTHER, V11, P328
[6]  
HAMILL RL, 1964, J ANTIBIOT, V17, P133
[7]   SYNTHESIS AND EVALUATION OF TYLOSIN-RELATED MACROLIDES MODIFIED AT THE ALDEHYDE FUNCTION - A NEW SERIES OF ORALLY EFFECTIVE ANTIBIOTICS [J].
KIRST, HA ;
TOTH, JE ;
DEBONO, M ;
WILLARD, KE ;
TRUEDELL, BA ;
OTT, JL ;
COUNTER, FT ;
FELTYDUCKWORTH, AM ;
PEKAREK, RS .
JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (08) :1631-1641
[8]   SYNTHESIS AND ANTIMICROBIAL EVALUATION OF ACYL DERIVATIVES OF 16-MEMBERED MACROLIDE ANTIBIOTICS RELATED TO TYLOSIN [J].
KIRST, HA ;
DEBONO, M ;
TOTH, JE ;
TRUEDELL, BA ;
WILLARD, KE ;
OTT, JL ;
COUNTER, FT ;
FELTYDUCKWORTH, AM ;
PEKAREK, RS .
JOURNAL OF ANTIBIOTICS, 1986, 39 (08) :1108-1122
[9]   SYNTHESIS, ANTIMICROBIAL EVALUATION AND STRUCTURE-ACTIVITY-RELATIONSHIPS WITHIN 23-MODIFIED DERIVATIVES OF 5-O-MYCAMINOSYLTYLONOLIDE [J].
KIRST, HA ;
TOTH, JE ;
WIND, JA ;
DEBONO, M ;
WILLARD, KE ;
MOLLOY, RM ;
PASCHAL, JW ;
OTT, JL ;
FELTYDUCKWORTH, AM ;
COUNTER, FT .
JOURNAL OF ANTIBIOTICS, 1987, 40 (06) :823-842
[10]   INVITRO AND INVIVO EVALUATION OF C-20-MODIFIED AND C-23-MODIFIED DERIVATIVES OF TYLOSIN AGAINST VETERINARY PATHOGENS [J].
KIRST, HA ;
OSE, EE ;
TOTH, JE ;
WILLARD, KE ;
DEBONO, M ;
FELTYDUCKWORTH, AM ;
PEKAREK, RS .
JOURNAL OF ANTIBIOTICS, 1988, 41 (07) :938-948
12