VARIOUS HIPPOCAMPAL-LESIONS INDUCED BY MULTI-FRACTIONAL IBOTENIC ACID INJECTIONS AND AMYGDALA KINDLING IN RATS

被引：18

作者：

TANAKA, T ^{[1
]}

KONDO, S ^{[1
]}

HORI, T ^{[1
]}

TANAKA, S ^{[1
]}

YONEMASU, Y ^{[1
]}

机构：

[1] TOTTORI UNIV,SCH MED,DEPT NEUROSURG,YONAGO,TOTTORI 683,JAPAN

来源：

BRAIN RESEARCH | 1991年 / 559卷 / 01期

关键词：

KINDLING EFFECT; IBOTENIC ACID; AMYGDALA; HIPPOCAMPUS; DEGENERATIVE LESION;

D O I：

10.1016/0006-8993(91)90299-B

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Hippocampal degenerative lesions were made bilaterally by means of multiple ibotenic acid injections and development of amygdala kindling was studied. In groups with lesions in either bilateral dorsal or ventral hippocampus, stimulations required for kindling were almost the same as those of controls. In the group with lesion of the entire hippocampus, kindling development was remarkably slow especially in the early stage of the kindling process. However, kindling effect was finally established in all groups.

引用

页码：154 / 158

页数：5