HELICAL NICKEL(II) COMPLEXES AS MOBILE PHASE ADDITIVES IN THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF ALKYLAMINE ENANTIOMERS

被引：12
作者：
BAZYLAK, G
机构：
来源：
ANALYST | 1992年 / 117卷 / 09期
关键词：
CHIRAL SEPARATION; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; NICKEL(II) SQUARE-PLANAR COMPLEXES; DIAMINE SYNTHESIS; ALKYLAMINE ENANTIOMER SEPARATION;
D O I：
10.1039/an9921701429
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The addition of nickel(II) chelates of tetradentate Schiff bases differing slightly in molecular structure to a water-acetonitrile (80 + 20) mobile phase in reversed-phase high-performance liquid chromatography makes it possible to perform enantiomeric and diastereoisomeric separations of aliphatic mono- and diamines. The separation was achieved on an octadecylsilane stationary phase without derivatization of the starting amine, and the results were compared with those obtained by a gas chromatographic procedure. The influence of helical structure, hydrophobicity, concentration and adsorption of the chelates present in the chromatographic system on the separation of the solutes studied is discussed.
引用
收藏
页码：1429 / 1433
页数：5
相关论文
共 50 条
[41]   Novel reversed-phase high-performance liquid chromatography stationary phase with oligo(ethylene glycol) "click" to silica [J].
Guo, Zhimou ;
Liu, Yanfang ;
Xu, Junyan ;
Xu, Qing ;
Xue, Xingya ;
Zhang, Feifang ;
Ke, Yanxiong ;
Liang, Xinmiao ;
Lei, Aiwen .
JOURNAL OF CHROMATOGRAPHY A, 2008, 1191 (1-2) :78-82
[42]   A mechanistic study of geminal dicationic ionic liquids as mobile phase additives for improving the separation performance of high-performance liquid chromatography [J].
Guanglong Ding ;
Wenbing Zhang ;
Zhaopeng Zhang ;
Dong Guo ;
Gang Tang ;
Yanran Li ;
Jianqiang Li ;
Yongsong Cao .
Analytical and Bioanalytical Chemistry, 2017, 409 :4581-4592
[43]   A mechanistic study of geminal dicationic ionic liquids as mobile phase additives for improving the separation performance of high-performance liquid chromatography [J].
Ding, Guanglong ;
Zhang, Wenbing ;
Zhang, Zhaopeng ;
Guo, Dong ;
Tang, Gang ;
Li, Yanran ;
Li, Jianqiang ;
Cao, Yongsong .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 409 (19) :4581-4592
[44]   Optimization of selected chromatographic responses using a designed experiment at the fine-tuning stage in reversed-phase high-performance liquid chromatographic method development [J].
Mahesan, B ;
Lai, W .
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2001, 27 (06) :585-590
[45]   Determination of Enantiomer in Tofacitinib Citrate Using Reversed-Phase Chiral High-Performance Liquid Chromatography [J].
Wang, Xue ;
Jin, Bo ;
Wang, Zhijun ;
Guo, Kaijing ;
Zhang, Tingting ;
Ma, Chen .
SEPARATIONS, 2024, 11 (03)
[46]   Simultaneous estimation of mometasone furoate and olopatadine hydrochloride by reversed-phase high-performance liquid chromatography [J].
Patel, Bhoomi ;
Patel, Ruchi .
SEPARATION SCIENCE PLUS, 2024, 7 (07)
[47]   THE ANALYTICAL PROFILE OF RUFLOXACIN, A NEW FLUOROQUINOLONE, BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
QUAGLIA, MG ;
FARINA, A ;
MELCHIORRE, P ;
BOSSU, E ;
PAGELLA, P .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1990, 8 (8-12) :1075-1078
[48]   DETERMINATION OF THEORETICAL RETENTION TIMES FOR PEPTIDES ANALYZED BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY [J].
Dziuba, Jerzy ;
Minkiewicz, Piotr ;
Mogut, Damir .
ACTA SCIENTIARUM POLONORUM-TECHNOLOGIA ALIMENTARIA, 2011, 10 (02) :209-221
[49]   Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus [J].
López, S ;
Bastida, J ;
Viladomat, F ;
Codina, C .
PHYTOCHEMICAL ANALYSIS, 2002, 13 (06) :311-315
[50]   SOLID-PHASE EXTRACTION AND DIRECT HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF CELIPROLOL IN PLASMA [J].
ROSTOCK, G ;
GUNZEL, R ;
GLOCKL, D .
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 1992, 30 (11) :512-513
12345