CRYSTAL-STRUCTURE OF 3-METHOXY-ESTRA-1,3,5(10)TRIENE-16-ALPHA-BR,17-ALPHA-OH

被引：1
作者：
SZULZEWSKY, K
机构：
来源：
KRISTALL UND TECHNIK-CRYSTAL RESEARCH AND TECHNOLOGY | 1979年 / 14卷 / 12期
关键词：
D O I：
10.1002/crat.19790141206
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The steroid 3‐Methoxy‐estra‐1,3,5(10)triene‐16αBr,17αOH crystallizes in the orthorhombic space group P 212121 with lattice constants a = 30.653(5) Å, b = 9.039(2) Å, c = 6.098(1) Å. The single molecule has an intramolecular OH… Br interaction. Intermolecular interactions are only of van der Waals type. Ring A is nearly planar, ring B has a nearly half chair conformation, ring C has a chair conformation and ring D an envelope conformation. Copyright © 1979 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
引用
收藏
页码：1445 / 1451
页数：7
相关论文
共 50 条
[31]   SYNTHESIS OF RACEMIC-3-METHOXY-17BETA-HYDROXY-1,3,5(10)-ESTRATRIENE-17ALPHA-CARBOXYLIC ACID AND OF 3-METHOXY-17ALPHA-HYDROXY-1,3,5(10)-ESTRATRIENE-17BETA-CARBOXYLIC ACID [J].
PREZEWOWSKY, K ;
WIECHERT, R .
ANNALEN DER CHEMIE-JUSTUS LIEBIG, 1971, 752 (NOCT) :68-+
[32]   CRYSTAL AND MOLECULAR-STRUCTURE OF (+/-)-3-METHOXY-B-NOR-9BETA-ESTRA-1,3,5(10)-TRIEN-17-ONE [J].
HANSON, JC ;
NORDMAN, CE .
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1975, 31 (FEB15) :493-496
[33]   Addition reactions at the 16(17) double bond of 3-methoxy-13α-estra-1,3,5(10),16-tetraene [J].
Mernyák, E ;
Schönecker, B ;
Lange, C ;
Kötteritzsch, M ;
Görls, H ;
Wölfling, J ;
Schneider, G .
STEROIDS, 2003, 68 (03) :289-295
[34]   HETEROCYCLIC-ANALOGS OF STEROIDS .15. CRYSTAL AND MOLECULAR-STRUCTURE OF (+/-)15-ALPHA-METHYL-13-ALPHA-8-AZA-16-OXA-ESTRA-1,3,5(10)-TRIENE-17-ONE, C17H21NO2 [J].
GALITSKII, NM ;
YASNITSKII, GA ;
GRITSUK, VI ;
LIS, LG ;
LAKHVICH, FA .
JOURNAL OF STRUCTURAL CHEMISTRY, 1987, 28 (06) :897-901
[35]   STEROIDS .48. 16-ALPHA-HETEROSUBSTITUTED 3-METHOXYESTRA-1,3,5(10)-TRIENE-17BETA-OLS [J].
SCHONECKER, B ;
PONSOLD, K .
JOURNAL FUR PRAKTISCHE CHEMIE, 1976, 318 (03) :483-488
[36]   D-Secoestrone derivatives. V. 3-Methoxy-17-oxo-17-phenyl-16,17-secoestra-1,3,5(10)-triene-16-nitrile and 17-hydroxy-3-methoxy-17-phenyl-16,17-secoestra-1,3,5(10)-triene-16-nitrile [J].
Lazar, D ;
Stankovic, S ;
Pejanovic, V ;
Courseille, C .
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2002, 58 :o63-o65
[37]   BIOTRANSFORMATION OF STS-267 (16ALPHA-AZIDO-3-METHOXY-ESTRA-1,3,5(10)-TRIEN-17-ONE) - EPIMERIZATION OF AN 16-ALPHA-AZIDO GROUP - A NEW METABOLIC REACTION IN THE RAT-LIVER [J].
SCHUMANN, W .
PHARMAZIE, 1988, 43 (05) :329-332
[38]   SYNTHESIS OF 17ALPHA-CH2X SUBSTITUTED ESTRA-1,3,5(10)-TRIENES [J].
HUBNER, M .
PHARMAZIE, 1973, 28 (11-1) :795-795
[39]   17ALPHA-N-PROPYL- AND 17ALPHA-ISOPROPYLESTRA-1,3,5[10)-TRIENE-3,17BETA-DIOL [J].
HUFFMAN, MN ;
REICH, H ;
STACY, RD .
JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1967, 12 (01) :144-&
[40]   SYNTHESIS OF ESTRA-1,3,5(10)-TRIEN-3,15ALPHA,16ALPHA,17BETA-TETROL - A NEW METABOLITE OF ESTRADIOL [J].
FISHMAN, J ;
GUZIK, H .
TETRAHEDRON LETTERS, 1967, (30) :2929-&
12345