MOLECULAR REQUIREMENTS FOR THE ADHESION AND SPREADING OF HAMSTER FIBROBLASTS

被引：118

作者：

HUGHES, RC ^{[1
]}

PENA, SDJ ^{[1
]}

CLARK, J ^{[1
]}

DOURMASHKIN, RR ^{[1
]}

机构：

[1] MRC,CLIN RES CTR,HARROW HA1 3UJ,MIDDLESEX,ENGLAND

来源：

EXPERIMENTAL CELL RESEARCH | 1979年 / 121卷 / 02期

关键词：

D O I：

10.1016/0014-4827(79)90009-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hamster plasma fibronectin adsorbs rapidly to a plastic surface to form a monolayer that promotes attachment and spreading of baby hamster kidney (BHK) fibroblasts. Maximal spreading requires a minimum surface density of about 1.8 × 1010 fibronectin molecules/cm2 indicating a maximum of 45 000 contacts between a well-spread cell and the adsorbed fibronectin lattice. Surfaces coated with other antibodies or lectins reactive with the BHK cell surface also promote rapid cell flattening. © 1979.

引用

页码：307 / 314

页数：8

共 24 条

[1] CONTROL OF MESSENGER-RNA PRODUCTION, TRANSLATION AND TURNOVER IN SUSPENDED AND REATTACHED ANCHORAGE-DEPENDENT FIBROBLASTS [J].