UNUSUALLY FACILE RING-OPENING OF 5-ALKOXYOXAZOLES - APPLICATION TO THE SYNTHESIS OF DIMETHOXY-ALPHA-METHYLDOPA

被引：34

作者：

JACOBI, PA

UENG, S

CARR, D

机构：

[1] Hall-Atwater Laboratories, Wesleyan University, Middletown

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 12期

关键词：

D O I：

10.1021/jo01326a039

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of n-BuLi, 5-alkoxyoxazoles undergo an unusually facile ring-opening reaction leading directly to lithiated isocyanoacetic acid derivatives, which in turn are versatile intermediates for the preparation of a variety of heterocyclic systems and amino acid derivatives. © 1979, American Chemical Society. All rights reserved.

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页码：2042 / 2044

页数：3

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