TUMOR-CYTOTOXICITY AND PRODUCTION OF INTERLEUKIN-1 AND TUMOR-NECROSIS-FACTOR FROM BLOOD MONOCYTES OF CERVICAL-CARCINOMA PATIENTS

被引：0

作者：

NADKARNI, JJ

DE, AK

JHAVER, KJ

KAMAT, MR

机构：

来源：

NEOPLASMA | 1994年 / 41卷 / 02期

关键词：

CERVICAL CARCINOMA; CYTOTOXICITY; INTERFERON-GAMMA; INTERLEUKIN-1; MONOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To assess the functional integrity of monocytes in patients with cervical carcinoma, cytotoxic potential of peripheral blood monocytes and their ability to secrete interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) after activation with different stimulating agents were studied. Comparable Levels of monocyte-mediated cytotoxicity were observed in healthy donors and patients. The production of IL-1 and TNF-alpha by monocytes of healthy donors and patients was similar indicating no defect in monocyte functions in these patients.

引用

页码：123 / 128

页数：6

共 38 条

[1] THE CELL BIOLOGY OF MACROPHAGE ACTIVATION
ADAMS, DO
HAMILTON, TA
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 1984, 2 : 283 - 318
[2] BALKWILL F, 1987, LANCET, V2, P1229
[3] DE AK, 1991, NEOPLASMA, V38, P493
[4] EVALUATION OF CIRCULATING TUMOR-NECROSIS-FACTOR-ALPHA IN PATIENTS WITH GYNECOLOGICAL MALIGNANCIES
DEJACO, P
ASSELAIN, B
ORLANDI, C
FRIDMAN, WH
TEILLAUD, JL
[J]. INTERNATIONAL JOURNAL OF CANCER, 1991, 48 (03) : 375 - 378
[5] DINARELLO CA, 1989, CRIT REV IMMUNOL, V9, P1
[6] MECHANISM OF INVITRO ANTITUMOR EFFECTS OF INTERLEUKIN-1 (IL 1)
ENDO, Y
MATSUSHIMA, K
OPPENHEIM, JJ
[J]. IMMUNOBIOLOGY, 1986, 172 (3-5) : 316 - 322
[7] A HIGHLY SENSITIVE CELL-LINE, WEHI-164 CLONE 13, FOR MEASURING CYTOTOXIC FACTOR TUMOR-NECROSIS-FACTOR FROM HUMAN-MONOCYTES
ESPEVIK, T
NISSENMEYER, J
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1986, 95 (01) : 99 - 105
[8] THE IMMUNOLOGICAL NETWORK AT THE SITE OF TUMOR REJECTION
EVANS, R
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1986, 865 (01) : 1 - 11
[9] HUMAN-MONOCYTES TUMORICIDAL ACTIVITY - THE ROLE OF INTERFERON-GAMMA AND BACTERIAL LIPOPOLYSACCHARIDE IN ITS STIMULATION, PRESERVATION AND DECAY
FISCHER, DG
RUBINSTEIN, M
[J]. IMMUNOBIOLOGY, 1986, 172 (1-2) : 110 - 119
[10] DEFICIENT PRODUCTION OF TUMOR-NECROSIS-FACTOR BY PERIPHERAL-BLOOD MONOCYTES IN CHRONIC LYMPHOCYTIC-LEUKEMIA
FLIEGER, D
EMMERICH, B
MEYER, N
RIETHMULLER, G
ZIEGLERHEITBROCK, HWL
[J]. INTERNATIONAL JOURNAL OF CANCER, 1990, 45 (02) : 280 - 286

← 1 2 3 4 →