IMPROVED PRACTICAL SYNTHESIS OF A PROSTAGLANDIN AND CARBOCYCLIC NUCLEOSIDE SYNTHON

被引：15
作者：
HUDLICKY, T
NATCHUS, MG
NUGENT, TC
机构：
[1] Department of Chemistry, Virginia Polytechnic Institute and State University, Virginia 24061, Blacksburg
来源：
SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1080/00397919208021086
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient, four step synthesis of chiral enone 2a [(+)-2,3-(isopropylidenedioxy)-4-cyclopentenone] from diol 1a (X = Cl), available from microbial oxidation of chlorobenzene, is described. This synthesis is a vast improvement over that previously reported and compares very favorably with others in the literature.
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页码：151 / 157
页数：7
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