A FACILE ROUTE TO IMIDAZOL-4-YL ANIONS AND THEIR REACTION WITH CARBONYL-COMPOUNDS

被引：73

作者：

TURNER, RM

LINDELL, SD

LEY, SV

机构：

[1] SCHERING AGROCHEM LTD,CHESTERFORD PK RES STN,WALDEN CB10 1XL,ESSEX,ENGLAND

[2] IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 20期

关键词：

D O I：

10.1021/jo00020a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of N-protected 4-iodoimidazoles 1-3 in CH2Cl2 solution with an ethereal solution of ethyl-magnesium bromide generates the corresponding imidazol-4-yl anions, which react with carbonyl compounds to give carbinols 4-14 in 60-83% yield.

引用

页码：5739 / 5740

页数：2

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