DETECTION OF H-2DB ANTIGEN ON OSMOTIC SHOCK-TREATED FRIEND-LEUKEMIA VIRUS-PARTICLES

被引:15
作者
CHEN, S
LILLY, F
机构
[1] Department of Genetics, Albert Einstein College of Medicine, Bronx, 10461, New York
关键词
D O I
10.1007/BF01570390
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Antisera specific for either H-2Kb, H-2Db, H-2Kk or H-2Dk antigenic determinants were examined for their capacity to neutralize Friend virus (FV) collected from the serum of infected H-2b/H-2k heterozygous mice. Neutralizing activity was detected (1) only with anti-H-2Db antisera, (2) only when the surface of virus particles had been mildly deranged by osmotic shock treatment and (3) only in the assay for the defective spleen focus-forming virus component of FV. © 1979 Springer-Verlag New York Inc.
引用
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页码:25 / 31
页数:7
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