POLYMORPHIC DRUG OXIDATION - PHARMACOKINETIC BASIS AND COMPARISON OF EXPERIMENTAL INDEXES

被引：76

作者：

JACKSON, PR ^{[1
]}

TUCKER, GT ^{[1
]}

LENNARD, MS ^{[1
]}

WOODS, HF ^{[1
]}

机构：

[1] UNIV SHEFFIELD,ROYAL HALLAMSHIRE HOSP,DEPT THERAPEUT,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1986年 / 22卷 / 05期

关键词：

D O I：

10.1111/j.1365-2125.1986.tb02933.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：541 / 550

页数：10

共 21 条

[1]

ANGELO M, 1975, BRIT J PHARMACOL, V55, pP264

[2] GAUSSIAN PSEUDO-RANDOM NUMBER GENERATOR [J].

BRENT, RP .

COMMUNICATIONS OF THE ACM, 1974, 17 (12) :704-706

[3] POLYMORPHIC HYDROXYLATION OF PERHEXILINE-MALEATE IN MAN [J].

COOPER, RG ;

EVANS, DAP ;

WHIBLEY, EJ .

JOURNAL OF MEDICAL GENETICS, 1984, 21 (01) :27-33

[4]

EICHELBAUM M, 1982, CLIN PHARMACOKINET, V7, P1, DOI 10.2165/00003088-198207010-00001

[5] A FAMILY AND POPULATION STUDY OF THE GENETIC-POLYMORPHISM OF DEBRISOQUINE OXIDATION IN A WHITE BRITISH-POPULATION [J].

EVANS, DAP ;

MAHGOUB, A ;

SLOAN, TP ;

IDLE, JR ;

SMITH, RL .

JOURNAL OF MEDICAL GENETICS, 1980, 17 (02) :102-105

[6]

IDLE JR, 1984, 2ND P WORLD C CLIN P, P148

[7] DEBRISOQUINE HYDROXYLATION CAPACITY - PROBLEMS OF ASSESSMENT IN 2 POPULATIONS [J].

INABA, T ;

OTTON, SV ;

KALOW, W .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (02) :218-223

[8] LACK OF EVIDENCE FOR POLYMORPHISM IN METOPROLOL METABOLISM [J].

JACK, DB ;

WILKINS, M ;

QUARTERMAN, CP .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 16 (02) :188-190

[9]

JOHANSSON KA, 1974, ACTA PHARM SUEC, V11, P333

[10] OXIDATION PHENOTYPE - A MAJOR DETERMINANT OF METOPROLOL METABOLISM AND RESPONSE [J].

LENNARD, MS ;

SILAS, JH ;

FREESTONE, S ;

RAMSAY, LE ;

TUCKER, GT ;

WOODS, HF .

NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (25) :1558-1560

← 1 2 3 →