Systemic Lupus Erythematosus Presenting as Corneal Perforation

被引：0

作者：

Chen, Hung-Chi Jesse ^{[1
,2
]}

Cheng, Ju-Chuan ^{[3
]}

Hsiao, Ching-Hsi ^{[1
]}

Ma, David Hui-Kang ^{[1
,4
]}

机构：

[1] Chang Gung Mem Hosp, Dept Ophthalmol, 5 Fushing St, Taoyuan, Taiwan

[2] Chang Gung Univ, Grad Inst Clin Med Sci, Taoyuan, Taiwan

[3] Cathay Gen Hosp Shijhih, Dept Ophthalmol, Taipei, Taiwan

[4] Chang Gung Univ, Coll Med, Dept Chinese Med, Taoyuan, Taiwan

来源：

TZU CHI MEDICAL JOURNAL | 2009年 / 21卷 / 02期

关键词：

Antinuclear antibody; Corneal perforation; Peripheral ulcerative keratopathy; Systemic lupus erythematosus; Therapeutic penetrating keratoplasty;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disorder that can have numerous ocular manifestations, which may precede or occur upon initial presentation of SLE. We report on a 72-year-old woman with peripheral corneal perforation but without any predisposing factors. SLE was diagnosed because of signs and symptoms such as arthritis, leukopenia, anemia, positive anti-dsDNA antibody, and positive antinuclear antibody (ANA). Systemic therapy with oral hydroxylchloroquine 200 mg daily was prescribed. Therapeutic penetrating keratoplasty with cryopre-served cornea was also performed to repair the perforated cornea. Six months postoperatively, the corneal lesion became scarred and her visual acuity improved from 2/200 to 20/70 without any ocular or systemic recurrence.

引用

页码：169 / 171

页数：3

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