SELECTIVE LIPASE-CATALYZED 6-O-ACYLATION OF ALKYL ALPHA-D-GLUCOPYRANOSIDES USING FUNCTIONALIZED ETHYL-ESTERS

被引：0

作者：

DEGOEDE, ATJW

BENCKHUIJSEN, W

VANRANTWIJK, F

MAAT, L

VANBEKKUM, H

机构：

来源：

RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY | 1993年 / 112卷 / 11期

关键词：

WATERACTIVITY; ESTERIFICATION; TRANSESTERIFICATION; ZEOLITE; ACRYLIC;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alkyl alpha-D-glucopyranosides were selectively converted into their 6-O-acyl esters by lipase-catalyzed transesterification with ethyl acrylate or ethyl 4-chlorobutanoate. Comparison of six lipase preparations showed large differences in activity and selectivity. The addition of zeolite CaA for selective adsorption of ethanol and water, exerted profound effects on conversion and regioselectivity of the transesterification. A quantitative conversion with high selectivity was achieved using lipases from C antarctica in the presence of zeolite CaA.

引用

页码：567 / 572

页数：6