SYNTHESIS AND HYDROLYSIS OF NEW ASPIRIN-DERIVED AND TRIFLUSAL-DERIVED ORTHO ESTERS AND ANHYDRIDES

被引：5

作者：

FALBORG, L ^{[1
]}

SENNING, A ^{[1
]}

机构：

[1] AARHUS UNIV, DEPT CHEM, DK-8000 AARHUS, DENMARK

来源：

ACTA CHEMICA SCANDINAVICA | 1993年 / 47卷 / 05期

关键词：

D O I：

10.3891/acta.chem.scand.47-0514

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ten new 2-substituted 2-methyl-2-oxy-4H-1,3-benzodioxin-4-ones, 4a-i and 6, have been synthesized and their rate constants of pseudo-first-order non-enzymatic hydrolysis determined. One of the compounds, 2-(2-acetoxybenzoyloxy)-2-methyl-4H-1,3-benzodioxin-4-one, 6, is a new anhydride of aspirin. The analogous triflusal derivative, 10, has also been synthesized.

引用

页码：514 / 520

页数：7

共 23 条

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[10]

HAZELL RG, IN PRESS

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