THYMUS AND REPRODUCTION - SEX-LINKED DYSGENESIA OF GONAD AFTER NEONATAL THYMECTOMY IN MICE

被引：435
作者：
NISHIZUK.Y
SAKAKURA, T
机构：
[1] Laboratory of Experimental Pathology, Aichi Cancer Center Research Institute, Chikusa-ku
来源：
SCIENCE | 1969年 / 166卷 / 3906期
关键词：
D O I：
10.1126/science.166.3906.753
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Neonatal thymectomy of mice, when no ectopic thymus existed, constantly resulted in developmental arrest of the ovary but not of the testis; it also caused sterility in the female. The ovaries of thymectomized mice were extremely small and were characterized by absence of follicles and corpora lutea. Such an ovarian dysgenesia was observed when the mice were thymectomized at 3 days of age, but not at 7 days or later; it was prevented by thymus grafting.
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页码：753 / &
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