SOLID-PHASE N-GLYCOPEPTIDE SYNTHESIS USING ALLYL SIDE-CHAIN PROTECTED FMOC-AMINO ACIDS

被引：31
|
作者：
KATES, SA
DELATORRE, BG
ERITJA, R
ALBERICIO, F
机构：
[1] MILLIPORE CORP,BEDFORD,MA 01730
[2] CSIC,CID,E-08034 BARCELONA,SPAIN
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 07期
关键词：
GLYCOPEPTIDES; ALLYL ESTERS; ORTHOGONAL PROTECTION; SOLID-PHASE SYNTHESIS;
D O I：
10.1016/S0040-4039(00)79958-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A method for the preparation of glycopeptides using a three-dimensional orthogonal solid-phase strategy (Fmoc/tBu/allyl) with selective allyl removal and direct coupling of glycosylamines to the carboxyl function while the peptide is attached to the resin is described.
引用
收藏
页码：1033 / 1034
页数：2
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