MMPI MEASURES OF IMPULSIVITY AND DEPRESSION CORRELATE WITH CSF 5-HIAA AND HVA IN DEPRESSION BUT NOT SCHIZOPHRENIA

被引：25

作者：

FAUSTMAN, WO ^{[1
]}

KING, RJ ^{[1
]}

FAULL, KF ^{[1
]}

MOSES, JA ^{[1
]}

BENSON, KL ^{[1
]}

ZARCONE, VP ^{[1
]}

CSERNANSKY, JG ^{[1
]}

机构：

[1] STANFORD UNIV, MED CTR, SCH MED, DEPT PSYCHIAT & BEHAV SCI, STANFORD, CA 94305 USA

来源：

JOURNAL OF AFFECTIVE DISORDERS | 1991年 / 22卷 / 04期

关键词：

CSF; 5-HIAA; DEPRESSION; IMPULSIVITY; MMPI; CSF HVA; SCHIZOPHRENIA;

D O I：

10.1016/0165-0327(91)90069-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recent studies have linked impulsivity with CSF concentrations of both 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA). One work found a negative correlation between the MMPI psychopathic deviate (Pd) scale and 5-HIAA in personality disordered men (Brown et al., 1982). We found that the 5-HIAA/Pd correlation extends (P < 0.05) to unmedicated depressed patients (n = 21). A trend was found between HVA and Pd in depression. There was no relationship between either metabolite and the Pd scale in unmedicated schizophrenics (n = 24). A significant inverse correlation was found between the MMPI depression scale and CSF HVA but not 5-HIAA in the depressed patients.

引用

页码：235 / 239

页数：5

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