PRESYNAPTIC ALPHA-2-ADRENOCEPTOR AND KAPPA-OPIATE RECEPTOR OCCUPANCY PROMOTES CLOSURE OF NEURONAL (N-TYPE) CALCIUM CHANNELS

被引：40
作者：
ADAMSON, P [1 ]
XIANG, JZ [1 ]
MANTZOURIDES, T [1 ]
BRAMMER, MJ [1 ]
CAMPBELL, IC [1 ]
机构：
[1] INST PSYCHIAT,DEPT BIOCHEM,LONDON SE5 8AF,ENGLAND
来源：
EUROPEAN JOURNAL OF PHARMACOLOGY | 1989年 / 174卷 / 01期
关键词：
D O I：
10.1016/0014-2999(89)90874-1
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：63 / 70
页数：8
相关论文
共 26 条
[1]   SYNAPTOSOMAL FREE [CA-2+] IS REDUCED BY CLONIDINE AND DYNORPHIN-A-(1-13) AND INCREASED BY IDAZOXAN [J].
ADAMSON, P ;
MCWILLIAM, JR ;
BRAMMER, MJ ;
CAMPBELL, IC .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 142 (02) :261-266
[2]   CYCLIC-AMP ANALOGS POTENTIATE KAPPA-OPIATE AND ATTENUATE ALPHA-2-ADRENOCEPTOR AGONIST EFFECTS ON INTRASYNAPTOSOMAL FREE CALCIUM [J].
ADAMSON, P ;
BRAMMER, MJ ;
CAMPBELL, IC .
JOURNAL OF NEUROCHEMISTRY, 1988, 51 (02) :542-547
[3]   MUTUAL ANTAGONISM OF KAPPA-OPIATE AND ALPHA-2-ADRENOCEPTOR AGONIST EFFECTS ON INTRASYNAPTOSOMAL FREE [CA-2+]I [J].
ADAMSON, P ;
MCWILLIAM, JR ;
BRAMMER, MJ ;
CAMPBELL, IC .
JOURNAL OF NEUROCHEMISTRY, 1988, 50 (01) :65-68
[4]   MEASUREMENT OF INTRASYNAPTOSOMAL FREE CALCIUM BY USING THE FLUORESCENT INDICATOR QUIN-2 [J].
ASHLEY, RH ;
BRAMMER, MJ ;
MARCHBANKS, R .
BIOCHEMICAL JOURNAL, 1984, 219 (01) :149-158
[5]   FUNCTIONAL BASIS FOR CLASSIFICATION OF ALPHA-ADRENERGIC RECEPTORS [J].
BERTHELSEN, S ;
PETTINGER, WA .
LIFE SCIENCES, 1977, 21 (05) :595-606
[6]   A RAPID METHOD FOR ISOLATION OF SYNAPTOSOMES ON PERCOLL GRADIENTS [J].
DUNKLEY, PR ;
JARVIE, PE ;
HEATH, JW ;
KIDD, GJ ;
ROSTAS, JAP .
BRAIN RESEARCH, 1986, 372 (01) :115-129
[7]  
Edgington E.S., 1980, RANDOMIZATION TESTS
[8]   IDAZOXAN (RX-781094) SELECTIVELY ANTAGONIZES ALPHA-2-ADRENOCEPTORS ON RAT CENTRAL NEURONS [J].
FREEDMAN, JE ;
AGHAJANIAN, GK .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 105 (3-4) :265-272
[9]  
GRAY EG, 1962, J ANAT, V96, P97
[10]   DYNORPHIN-A SELECTIVELY REDUCES A LARGE TRANSIENT (N-TYPE) CALCIUM CURRENT OF MOUSE DORSAL-ROOT GANGLION NEURONS IN CELL-CULTURE [J].
GROSS, RA ;
MACDONALD, RL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (15) :5469-5473
123