SYNTHESIS OF 2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLES

被引：11
作者：
KAUGARS, G
MARTIN, SE
NELSON, SJ
WATT, W
机构：
[1] Animal Health Discovery Research, Upjohn Laboratories, The Upjohn Company, Kalamazoo
[2] Physical and Analytical Chemistry, Upjohn Laboratories, The Upjohn Company, Kalamazoo
来源：
HETEROCYCLES | 1994年 / 38卷 / 12期
关键词：
D O I：
10.3987/COM-94-6838
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reactions of 2-amino-2-thiazoline with alkylating and acylating agents give initial reaction on the endocyclic nitrogen. Acyl groups, however, readily rearrange to the exocyclic nitrogen to give the products usually observed in these reactions. These observations clear up a considerable amount of confusion in the literature and lead to the efficient synthesis of 2,3,5,6-tetrahydroimidazo[2,1-b]thiazoles.
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页码：2593 / 2603
页数：11
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