PROFILING OF UREMIC SERUM BY HIGH-RESOLUTION GAS CHROMATOGRAPHY-ELECTRON-IMPACT, CHEMICAL IONIZATION MASS-SPECTROMETRY

被引：29

作者：

SCHOOTS, AC ^{[1
]}

MIKKERS, FEP ^{[1
]}

CRAMERS, CAMG ^{[1
]}

RINGOIR, S ^{[1
]}

机构：

[1] STATE UNIV GHENT HOSP,DEPT MED,DIV NEPHROL,B-9000 GHENT,BELGIUM

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 164卷 / 01期

关键词：

D O I：

10.1016/S0378-4347(00)81565-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A fast and reliable procedure for gas chromatographic profiling of components in ultrafiltrated uremic serum has been developed, using glass capillary columns. Sample pretreatment consists of ultrafiltration, evaporation and silylation. Some twenty components are identified by electron-impact and chemical ionization mass spectrometry. A comparison is made between profiles of sera from a series of uremic patients, before and after hemodialysis, and from non-uremic sera. Significant differences are found between these profiles. A dialysis ratio" is introduced as a parameter for the removal of retained components by hemodialysis treatment. © 1979."

引用

页码：1 / 8

页数：8

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