Bioactive polysaccharides from Momordica charantia as functional ingredients: a review of their extraction, bioactivities, structural-activity relationships, and application prospects

被引:0
作者
Zheng, Jiamei [1 ]
Shang, Mingyue [1 ]
Dai, Guona [1 ]
Dong, Jingjing [1 ]
Wang, Yaping [1 ,2 ]
Duan, Baozhong [1 ]
机构
[1] Dali Univ, Coll Pharmaceut Sci, Dali, Peoples R China
[2] Jinan Univ, Formula Pattern Res Ctr, Sch Tradit Chinese Med, Guangzhou, Guangdong, Peoples R China
关键词
Momordica charantia polysaccharides (MCPs); functional ingredients; structural features; bioactivities; structure-activity relationship; application;
D O I
暂无
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Momordica charantia L. is a well-known medicine and food homology plant with high pharmaceutical and nutritional values. Polysaccharides are carbohydrate polymers connected by glycosidic bonds, one of the key functional ingredients of M. charantia. Recently, M. charantia polysaccharides (MCPs) have attracted much attention from industries and researchers due to their anti-oxidant, anti-tumor, anti-diabetes, anti-bacteria, immunomodulatory, neuroprotection, and organ protection activities. However, the development and utilization of MCPs-based functional foods and medicines were hindered by the lack of a deeper understanding of the structure-activity relationship (SAR), structural modification, applications, and safety of MCPs. Herein, we provide an overview of the extraction, purification, structural characterization, bioactivities, and mechanisms of MCPs. Besides, SAR, toxicities, application, and influences of the modification associated with bioactivities are spotlighted, and the potential development and future study direction are scrutinized. This review provides knowledge and research underpinnings for the further research and application of MCPs as therapeutic agents and functional food additives.
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页数:24
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