ERRORS IN PROTEIN SYNTHESIS AND CLONAL SENESCENCE IN FUNGI

被引：92
作者：
HOLLIDAY, R
机构：
[1] National Institute for Medical Research
来源：
NATURE | 1969年 / 221卷 / 5187期
关键词：
D O I：
10.1038/2211224a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Irreversible senescence in fungi - a cytoplasmic condition - may be the result of a breakdown in the maintenance of the accuracy of protein synthesis. Premature senescence in Podospora can be induced by treatments which may reduce the accuracy of amino-acid incorporation. A predicted interrelationship between phenotypic reversion of a base substitution mutation, suppression and ageing is shown in Neurospora. © 1969 Nature Publishing Group.
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页码：1224 / &
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