IDENTIFICATION OF A NOVEL SUGAR, 4-AMINO-4,6-DIDEOXY-2-O-METHYLMANNOSE IN THE LIPOPOLYSACCHARIDE OF VIBRIO-CHOLERAE O1 SEROTYPE OGAWA

被引：64

作者：

ITO, T ^{[1
]}

HIGUCHI, T ^{[1
]}

HIROBE, M ^{[1
]}

HIRAMATSU, K ^{[1
]}

YOKOTA, T ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

CARBOHYDRATE RESEARCH | 1994年 / 256卷 / 01期

关键词：

D O I：

10.1016/0008-6215(94)84231-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel sugar in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa has been identified. The sugar was liberated from the lipopolysaccharide when hydrolyzed in 10 M HCl at 90-degrees-C for 15 min. The sugar was purified and identified as 4-amino-4,6-dideoxy-2-O-methylmannose (2-O-methylperosamine). Since it was found only in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa, it seems that the sugar is one of the specific constituents determining Ogawa serotype specificity.

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页码：113 / 128

页数：16

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