CLINICAL PHARMACOKINETICS IN THE TREATMENT OF RHEUMATOID-ARTHRITIS IN PREGNANCY

被引：4
作者：
WITTER, FR
机构：
[1] Johns Hopkins University School of Medicine, Baltimore, Maryland, 21287-1228
来源：
CLINICAL PHARMACOKINETICS | 1993年 / 25卷 / 06期
关键词：
D O I：
10.2165/00003088-199325060-00004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Rheumatoid arthritis is a relatively common problem in women of reproductive age. Pregnancy may affect all aspects of the pharmacokinetics of the drugs used in its treatment. The effects of pregnancy on the pharmacokinetics of drugs are, for the most part, not clinically significant. The pharmacokinetics of placental transfer and fetal safety have been specified for many drugs. Drugs used in rheumatoid arthritis can he classified into 3 classes: those with the greatest safety for the fetus, those that an unsafe for the fetus, and those for which there are insufficient data to determine the risk to the fetus.
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页码：444 / 449
页数：6
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