AN ATTEMPT TO PREPARE HEPATITIS-B VIRUS (HBV)-FREE PLASMA BY ULTRAFILTRATION USING MICROPOROUS REGENERATED CELLULOSE HOLLOW FIBER

被引：8

作者：

SEKIGUCHI, S

ITO, K

KOBAYASHI, M

IKEDA, H

MANABE, S

TSURUMI, T

ISHIKAWA, G

SATANI, M

YAMAGUCHI, K

机构：

[1] Hokkaido Red Cross Blood Center, Nishi-ku, Sapporo

[2] Asahi Chemical Industry Co. Ltd, Cniyodaku, Tokyo, Imperial Twr. 18F

[3] Institute of Laboratory Animals, Yamaguchi University School of Medicine, Ube, Yamaguchi

来源：

TRANSFUSION SCIENCE | 1990年 / 11卷 / 02期

关键词：

D O I：

10.1016/0955-3886(90)90097-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hepatitis B Virus(HBV) can be effectively removed from HBV-positive plasma by filtration with a Bemberg(R) Microporous Membrane (BMM) with a pore size of 30 nm or less, however considerable amounts of macromolecular IgM and Factor VIII are trapped in the BMM. We report that HBV-free plasma with adequate amounts of all of the plasma proteins can be obtained by double filtration with a BMM with a pore size of 50 nm. Thus, it may be possible to remove HBV or other transfusion-associated viruses from plasma by BMM filtration with good recovery of all of the plasma components.

引用

页码：211 / 216

页数：6

共 13 条

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