A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions

被引：38
作者：
Kodiyan, Joyson [1 ]
Amber, Kyle T. [2 ]
机构：
[1] Univ Miami, Miller Sch Med, Miami, FL 33136 USA
[2] Macneal Mem Hosp, Dept Med Educ, Berwyn, IL 60402 USA
来源：
ANTIOXIDANTS | 2015年 / 4卷 / 02期
关键词：
radiation induced skin toxicity; calendula; complementary and alternative medicine; radiodermatitis; radiation induced dermatitis; cancer;
D O I：
10.3390/antiox4020293
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong evidence in the laboratory supporting calendula's mechanism of action in preventing radiation induced skin toxicity, clinical studies have demonstrated mixed results. In light of the controversy surrounding the efficacy of calendula in treating and preventing radiodermatitis, the topic warrants further discussion.
引用
收藏
页码：293 / 303
页数：11
相关论文
共 68 条
[11]   CONTACT SENSITIZATION BY ALTERNATIVE TOPICAL MEDICAMENTS CONTAINING PLANT-EXTRACTS [J].
BRUYNZEEL, DP ;
VANKETEL, WG ;
YOUNG, E ;
VANJOOST, T ;
SMEENK, G .
CONTACT DERMATITIS, 1992, 27 (04) :278-279
[12]   Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - part 1: Achillea millefolium-Curcuma longa [J].
Calapai, Gioacchino ;
Miroddi, Marco ;
Minciullo, Paola L. ;
Caputi, Achille P. ;
Gangemi, Sebastiano ;
Schmidt, Richard J. .
CONTACT DERMATITIS, 2014, 71 (01) :1-12
[13]  
Campbell I R, 1992, Clin Oncol (R Coll Radiol), V4, P78, DOI 10.1016/S0936-6555(05)80971-9
[14]   TRANSFORMING GROWTH-FACTOR-BETA - A PROMOTOR OF LATE CONNECTIVE-TISSUE INJURY FOLLOWING RADIOTHERAPY [J].
CANNEY, PA ;
DEAN, S .
BRITISH JOURNAL OF RADIOLOGY, 1990, 63 (752) :620-623
[15]  
Chrystal Kathryn, 2003, N Z Med J, V116, pU296
[16]   Hypofractionated Radiotherapy Does Not Increase Acute Toxicity in Large-Breasted Women Results From a Prospectively Collected Series [J].
Corbin, Kimberly S. ;
Dorn, Paige L. ;
Jain, Supriya K. ;
Al-Hallaq, Hania A. ;
Hasan, Yasmin ;
Chmura, Steven J. .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2014, 37 (04) :322-326
[17]   TOXICITY CRITERIA OF THE RADIATION-THERAPY ONCOLOGY GROUP (RTOG) AND THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER (EORTC) [J].
COX, JD ;
STETZ, J ;
PAJAK, TF .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1995, 31 (05) :1341-1346
[18]   THE ALLERGENS IN COSMETICS [J].
DEGROOT, AC ;
BRUYNZEEL, DP ;
BOS, JD ;
VANDERMEEREN, HLM ;
VANJOOST, T ;
JAGTMAN, BA ;
WEYLAND, JW .
ARCHIVES OF DERMATOLOGY, 1988, 124 (10) :1525-1529
[19]   Preventing the acute skin side effects in patients treated with radiotherapy for breast cancer: the use of corneometry in order to evaluate the protective effect of moisturizing creams [J].
Di Franco, Rossella ;
Sammarco, Elena ;
Calvanese, Maria Grazia ;
De Natale, Flora ;
Falivene, Sara ;
Di Lecce, Ada ;
Giugliano, Francesca Maria ;
Murino, Paola ;
Manzo, Roberto ;
Cappabianca, Salvatore ;
Muto, Paolo ;
Ravo, Vincenzo .
RADIATION ONCOLOGY, 2013, 8
[20]   Mepilex Lite dressings for the management of radiation-induced erythema: a systematic inpatient controlled clinical trial [J].
Diggelmann, K. V. ;
Zytkovicz, A. E. ;
Tuaine, J. M. ;
Bennett, N. C. ;
Kelly, L. E. ;
Herst, P. M. .
BRITISH JOURNAL OF RADIOLOGY, 2010, 83 (995) :971-978
1234567