Therapeutic Whole-Lung Lavage for Pulmonary Alveolar Proteinosis A Procedural Update

被引:29
|
作者
Abdelmalak, Basem B. [1 ,2 ]
Khanna, Ashish K. [3 ]
Culver, Daniel A. [4 ]
Popovich, Marc J. [3 ]
机构
[1] Cleveland Clin, Dept Gen Anesthesiol, 9500 Euclid Ave,E31, Cleveland, OH 44195 USA
[2] Cleveland Clin, Dept Outcomes Res, Cleveland, OH USA
[3] Cleveland Clin, Anesthesiol Inst, Dept Crit Care Anesthesiol, Cleveland, OH 44106 USA
[4] Cleveland Clin, Resp Inst, Cleveland, OH 44106 USA
关键词
whole-lung lavage; pulmonary alveolar proteinosis; GM-CSF; interstitial lung disease;
D O I
10.1097/LBR.0000000000000180
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Pulmonary alveolar proteinosis is a disease caused by increased accumulation and impaired clearance of surfactant by alveolar macrophages. This narrative review summarizes the role of therapeutic whole-lung lavage in the management of pulmonary alveolar proteinosis. We describe the preprocedural evaluation, indications, and anesthetic considerations, along with step-by step technical aspects of the procedure, postoperative recovery, potential complications, and long-term outcomes.
引用
收藏
页码:251 / 258
页数:8
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