EFFECT OF POLYCATION BASED ON ALKALOID LUPININ-ANTIHEPOLIN AND ITS COMPLEX WITH HEPARIN ON DNA-SYNTHESIS IN RAT HEPATOCYTES

被引：0
作者：
MAKHSUDOVA, GT
GOLENCHENKO, VA
EFIMOV, VS
机构：
[1] Department of Hemostasis Pharmacology, Russian State Medical University, Moscow
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1994年 / 117卷 / 06期
关键词：
POLYCATIONS; HEPARIN; ANTIHEPOLIN; POLYCOMPLEX; HEPATOCYTES; DNA SYNTHESIS;
D O I：
10.1007/BF02444339
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The effect of the antiheparinate antihepolin on the intensity of replication processes in rat hepatocytes was studied. A single intravenous infusion of polycation caused an approximately 6-fold increase in the intensity of DNA synthesis on day 2 postinjection followed by a drop to the baseline level on days 5-6. If antihepolin was injected in parallel with heparin, DNA synthesis was intensified after just 24 hours.
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页码：631 / 633
页数：3
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