ALIPHATIC HYDROXYLATION BY HIGHLY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - EVIDENCE FOR A CARBON RADICAL INTERMEDIATE

被引：544

作者：

GROVES, JT ^{[1
]}

MCCLUSKY, GA ^{[1
]}

WHITE, RE ^{[1
]}

COON, MJ ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT BIOL CHEM,ANN ARBOR,MI 48109

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1978年 / 81卷 / 01期

关键词：

D O I：

10.1016/0006-291X(78)91643-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：154 / 160

页数：7

共 27 条

[11]

HAUGEN DA, 1975, J BIOL CHEM, V250, P3567

[12] INTRAMOLECULAR DETERMINATION OF PRIMARY KINETIC ISOTOPE EFFECTS IN HYDROXYLATIONS CATALYZED BY CYTOCHROME-P-450 [J].

HJELMELAND, LM ;

ARONOW, L ;

TRUDELL, JR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 76 (02) :541-549

[13] MASS-SPECTRUM AND FRAGMENTATION MECHANISM OF EXO-NORBORNEOL AND ENDO-NORBORNEOL [J].

HOLMES, JL ;

MCGILLIV.D .

ORGANIC MASS SPECTROMETRY, 1973, 7 (05) :559-572

[14] SODIUM PERIODATE, SODIUM-CHLORITE, ORGANIC HYDROPEROXIDES, AND H2O2 AS HYDROXYLATING AGENTS IN STEROID HYDROXYLATION REACTIONS CATALYZED BY PARTIALLY PURIFIED CYTOCHROME-P-450 [J].

HRYCAY, EG ;

GUSTAFSSON, JA ;

INGELMANSUNDBERG, M ;

ERNSTER, L .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 66 (01) :209-216

[15] DEHYDRATION OF BICYCLO[2.2.1]-2-HEPTANOLS IN MASS SPECTROMETER [J].

HUMSKI, K ;

KLASINC, L .

JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (20) :3057-&

[16] ANALYSIS OF MASS SPECTRAL FRAGMENTATION PATTERNS IN VARIOUS BICYCLIC ALCOHOLS [J].

KWART, H ;

BLAZER, TA .

JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (08) :2726-&

[17]

LU AYH, 1969, J BIOL CHEM, V244, P3714

[18]

LU AYH, 1970, MOL PHARMACOL, V6, P213

[19] MICROSOMAL OXYGENATION OF ETHYL BENZENE - ISOTOPIC, STREOCHEMICAL, AND INDUCTION STUDIES [J].

MCMAHON, RE ;

SULLIVAN, HR ;

CRAIG, JC ;

PEREIRA, WE .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1969, 132 (02) :575-&

[20] STUDIES ON HYDROPEROXIDE-DEPENDENT SUBSTRATE HYDROXYLATION BY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 [J].

NORDBLOM, GD ;

WHITE, RE ;

COON, MJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1976, 175 (02) :524-533

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